To study effect of Ayurvedic medicines in Migraine

Phase 2/3

Completed

• Conditions: Migraine, unspecified. Ayurveda Condition: ARDHAVABEDAKAH,

• Registration Number: CTRI/2022/05/042700
• Lead Sponsor: National Institute of Ayurveda Jaipur

Brief Summary

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|AIMS AND OBJECTIVES**Aim-** To conduct a randomized clinical trial on comparative efficacy of *Gandharyadi Ghrita Nasya* and *Dashmooladi Ghrita Nasya* along with *Dhatryadi Ghan Vati* in the management of *Ardhavbhedaka* with special reference to Migraine.

**Objectives-**

1.  To study and establish a conceptual correlation between *Ardhavabhedaka* and Migraine.

2.  To evaluate and compare the efficacy of trial drugs in *ardhavabhedaka* andMigraine*.*

RESEARCH QUESTIONWhether *Gandharyadi* *Ghrita* *Nasya* and *Dashmooladi* *Ghrita*  *Nasya*  along with *Dhatryadi Ghan Vati* are effective in the management of *Ardhavabhedaka*(Migraine)?

HYPOTHESISNULL HYPOTHESIS :

H0   -There is no effect of *Gandharyadi Ghrita Nasya* and *Dashmooladi Ghrita Nasya* along with *Dhatryadi Ghan Vati* in *Ardhavabhedaka*(Migraine).

 ALTERNATE HYPOTHESIS:

H1 - There is significant difference in the effect of *Gandharyadi Ghrita Nasya* and *Dashmooladi Ghrita Nasya* along with *Dhatryadi GhanVati* in *Ardhavabhedaka*(Migraine).

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-06
• Study Completion: 2022-12-30
• Last Update Posted: 2023-06-11

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 1.Patients willing to participate in this trial through written informed consent.
• 2.Both fresh and treated patients.
• 3.Patients between18 to 60 years of age from either sex.
• 4.Patients presenting with symptoms of Ardhavabhedaka vis-Ã -vis Migraine.

Exclusion Criteria

• 1.Patients of age less than 18 and greater than 60 2.Patients with referred pain in one half of head due to other secondary reasons such as anxiety, refractive errors etc.
• rather than migraine.
• 3.Patients with complicated Migraine like hemiplegic migraine and having any chronic debilitating disease with other neurological pathology.
• 4.Pregnant and lactating women.
• 5.Patients suffering from any other major systemic disorders which interfare with course of treatment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in intensity/ duration/ frequency of headache (MIDAS/ VAS)	30 days

Secondary Outcome Measures

Name	Time	Method
Changes in other associated symptoms of migraine:	1.Nausea

Trial Locations

Locations (1)

National Institute of Ayurveda (Deemed to be university) Jaipur; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute of Ayurveda (Deemed to be university) Jaipur

🇮🇳Jaipur, RAJASTHAN, India

Dr Mahima Choudhary

Principal investigator

9461267615

mahimachoudhary7615@gmail.com