NCT00157807终止不适用
Clinical and Economic Consequences of Left Atrial Bipolar Radiofrequency Ablation of Persistent and Permanent Atrial Fibrillation During Cardiac Surgery. A Prospective Randomized Multi Center Trial
Medtronic Cardiac Surgery10 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2005年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 24
- 试验地点
- 10
- 主要终点
- Quality of life
研究概览
简要总结
The clinical effects of intra-operative radiofrequency ablation in patients with persistent or permanent atrial fibrillation and an indication for an implantation of a heart valve prosthesis or coronary bypass surgery are the purposes of this study. The study will examine if and to what extent the quality of life and the use of medical care differs between patients with and without ablation. Furthermore, there will be thorough echocardiographic examinations of the heart to detect differences between the different treatment groups. The patients will be followed for one year after treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Persistent atrial fibrillation
- •Permanent atrial fibrillation
- •Mitral valve defect
- •Tricuspid valve defect
- •Aortic valve defect
- •Coronary artery disease
排除标准
- •Pregnancy
- •Age < 18 or > 75 Years
- •Emergency surgery
- •Left dominant coronary circulation (relative contraindication)
- •Coronary arteries of the posterior wall without pathological findings: No inclusion
- •Stenosis of the posterior wall vessels, supplied with a CABG (coronary artery bypass grafting): Inclusion possible
- •Left ventricular ejection fraction < 30%
- •Size of the left atrium > 7 cm
- •Thrombosis of the left atrial appendage
- •Leads in the coronary sinus
- •Atrial flutter
- •Infective endocarditis
- •Reoperation
- •Participation in other studies
- •Life expectancy of less than 12 months
- •Psychiatric disorders
- •Hyperthyreosis
结局指标
主要结局
Quality of life
时间窗: 12 months
Cost of care
时间窗: 12 months
次要结局
- Atrial fibrillation(12 months)
- Echo parameters(12 months)
研究者
研究点 (10)
Loading locations...
相似试验
已完成
不适用
Use of Radiofrequency Ablation to Eliminate Continuous Atrial Fibrillation in Patients Undergoing Mitral Valve SurgeryRadiofrequency Catheter AblationAtrial FibrillationNCT00238706University Hospitals, Leicester
招募中
不适用
Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT RegistryIschemic Stroke, AcuteAtrial FibrillationNCT06075628Kansas City Heart Rhythm Research Foundation100
已完成
不适用
Study on Left Atrial Function of Paroxysmal Supraventricular Tachycardia After Radiofrequency AblationParoxysmal Supraventricular TachycardiaNCT03348436Ruiqin xie100
尚未招募
3 期
Effect of surgery versus radiofrequency ablation method on treatment varicose veinsIRCT20120215009014N487Hamedan University of Medical Sciences50
已完成
不适用
Identification of Risk Factors for Atrial Fibrillation After Ablation of an Atrial Flutter by Radiofrequency of the Cavotricuspid Isthmus.FlutterNCT03919097José Castro50
