NCT04227717已完成不适用
Assessment of a Custom-Built MRI Coil for Spine Radiotherapy Treatment Planning
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Difference of calculated doses to the cauda equine and spinal cord based upon MRI coil vs CT myelogram used to define each structure
研究概览
简要总结
Participants will receive an MRI with a custom-built MRI coil for each participant. The purpose is to find out whether this custom-built MRI coil can help doctors see the different parts of the spine as well as or better than they can with standard CT myelograms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •>/= 18 years of age at the time of treatment
- •Able to give informed consent
- •Consented for spine stereotactic radiation therapy
- •No contraindications for CT myelograms which include:
- •Allergy to CT contrast
- •Use of phenothiazines
- •Platelet count < 60,000 K/mcl
- •INR > 1.5
- •VEGF inhibitor use in the past 2 weeks prior to myelogram
- •NSAID use in the past 5 days prior to myelogram
- •Renal disease
- •Creatinine > 1.2 mg/dL
- •No contraindications for MRI scans which include:
- •Newly placed glucose monitors
- •Tattoos (Tattoos for radiation therapy are allowed)
- •Presence of a cardiac pacemaker
- •Presence of an implanted cardioverter defibrillator
- •Breast tissue expander
- •Aneurysm clip
- •Any other implanted metallic (BB, bullet, shrapnel, IUD, metallic stent or filter, spinal cord simulator etc.) or electronic device which is considered MR unsafe
- •Severe claustrophobia or inability to lie flat for the duration of the study, etc.
排除标准
- •Presence of surgical spine hardware at the region of interest
- •Presence of cervical spine lesions
- •History of claustrophobia
结局指标
主要结局
Difference of calculated doses to the cauda equine and spinal cord based upon MRI coil vs CT myelogram used to define each structure
时间窗: 6 months
The calculated doses to the cauda equine and spinal cord will be compared and evaluated for significant difference based upon the imaging modality (MRI coil vs CT myelogram) used to define each structure, with all other target and avoidance volumes being equal in the same patient.
次要结局
未报告次要终点
研究者
研究点 (1)
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