Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Voluntary Patients

Not Applicable

Completed

• Conditions: Magnetic Resonance Imaging
• Interventions: Device: NIRS; Device: EEG; Radiation: Magnetic resonance imaging

• Registration Number: NCT03160235
• Lead Sponsor: University Hospital, Grenoble

Brief Summary

Studies that will be carried out on healthy volunteers will have as main objective the development and optimization of the parameters of sequences or the design of the paradigms of stimulation in order to optimize the quality and the relevance of the images realized taking in Taking account of anatomical, functional or metabolic parameters, or integrating new approaches resulting from technical evolutions

Detailed Description

The pathologies that interest us in these refinements concern mainly the chronic (or sequellar) brain disorders which can be degenerative, developmental or vascular. The patients who will be recruited will be known patients of our Service (University Clinic of Neuroradiology and MRI) that we follow during checks. The type of examination that will be applied to them, between MRI, EEG and NIRS, will be specified in the consent form. These examinations will not be invoiced either to the patient or to the social security, and the related costs will be borne by our Federative Research Structure or sometimes, when these explorations are upstream of a defined research protocol and funded, They will be financed under this protocol.

Study Timeline

• Study Start: 2013-02-01
• Study First Submitted: 2017-04-24
• Study First Submitted QC: 2017-05-17
• Study First Posted: 2017-05-19
• Primary Completion: 2021-07-08
• Study Completion: 2021-07-08
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-19
• Last Update Posted: 2021-10-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• major voluntary patients
• socially insured.
• Karnofsky score above 60%.
• given their consent.
• absence of contraindication to the MRI examination

Exclusion Criteria

• Subjects under the age of 18
• pregnant women
• persons referred to in articles L1121-5 to L1121-8 of the CSP.
• Patients with acute illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Development of NIRS protocols	NIRS	NIRS exam to grade differents interventions for future research
Development of EEG protocols	EEG	EEF exam to grade differents interventions for future research
Development of MRI protocols	Magnetic resonance imaging	MRI exam to grade differents interventions for future research

Primary Outcome Measures

Name	Time	Method
Spatial resolution of new MRI imaging sequences MRI scanning.	Two hours

Trial Locations

Locations (1)

CHU Grenoble-Alpes; 🇫🇷 Grenoble, France