efficacy of mesotherapy in the treatment of chronic radiculopathy

Phase 3

Conditions: chronic radiculopathy.
Radiculopathy, lumbosacral region
M54.17

Registration Number: IRCT20231203060255N1

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 60

Inclusion Criteria

1-Consent to participate in the study2- Patients with chronic radicular back pain due to a herniated disc (radicular pain for more than three months and confirming the diagnosis of a herniated disc as the cause of the symptoms by MRI and matching the patient's radicular symptoms with a herniated disc observed in the MRI according to the diagnosis of a physical medicine specialist3- Age above 18 years4- moderate and severe pain intensity (above 5 based on VAS)

Exclusion Criteria

1- Surgery in the last 3 months2- Rheumatological diseases or severe systemic diseases (diabetes,...)3-Neurological diseases (MS, neuropathy,...)4- History of mesotherapy in the last 3 months5- The presence of inflammation in the sacroiliac joint during examinations6- history of fracture in the spine7 presence of spondylolysis or spondylolisthesis8- Coagulation disorders (genetic disorders such as hemophilia or acquired disorders such as warfarin use)9- History of any type of cancer 10- Bone metabolic diseases such as Paget11- Anatomical abnormalities of the spine such as scoliosis12- History of any allergy to the drugs used (allergy to lidocaine or NSAID)13-Kidney failure14- Skin disease at the injection site15- Use of complementary treatments including acupuncture and herbal medicines 1 month before treatment or during treatment16-Drug addiction

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: Immediately after treatment, one month after treatment, two months after treatment. Method of measurement: Visual Analogue Scale.;Patient function. Timepoint: Immediately after treatment, one month after treatment, two months after treatment. Method of measurement: RMQ (Roland Morris Disability Questionnaire.

Secondary Outcome Measures