Role of Negative Pressure Wound Therapy in the Management of Diabetic Foot Ulcers
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 主要终点
- Management of diabetic foot ulcers.
研究概览
简要总结
Role of Negative Pressure Wound Therapy in the Management of Diabetic Foot Ulcers
• The aim of this study will be to assess negative pressure wound therapy in treating diabetic foot ulcers.
详细描述
Diabetic Foot ulcers are a major cause of admission in diabetic patients, and comprise a disproportionately high number of hospital days because of multiple surgical procedures and prolonged length of stay in Hospital.
The improvement in diabetes therapy and the reinforcement of guidelines have reduced the amputation rate. The approach to diabetic foot ulcers has allowed the availability of several medical options to ensure the best local condition and wound healing.
Negative-pressure wound therapy is a non-invasive therapy system that employs a controlled negative pressure using a vacuum device to promote wound healing by removing fluid from open wounds through a sealed dressing or a foam dressing connected to a container.
An earlier study has shown that NPWT reduced the need for subsequent amputations in a 6-month follow-up period. This reflects the importance of this device in management of DFUs and prevents its complications.
As most of the diabetic wounds present with infection, the success of NPWT is still highly dependent upon the adequacy of surgical debridement and antimicrobial coverage.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute and chronic diabetic wounds, pressure ulcers.
- •Wagener's Grade I superficial diabetic ulcer.
- •Wagener's Grade II after surgical debridement and an appropriate antibiotic therapy.
- •Ischemic wounds after revascularization.
排除标准
- •- Wagener's Grade III, osteomyelitis and Charcot's joint septic arthritis.
- •Wagener's Grade IV, localized gangrene e.g. toe ,heel.
- •Wagener's Grade V, extensive gangrene involving the whole foot.
- •Septicemia. .
- •Gas forming organism.
- •Wounds resulting from venous insufficiency.
- •Peripheral vascular disease (absent distal pulse).
- •Patients being treated with corticosteroids, immunosuppressive drugs or chemotherapy
- •Any other serious pre-existing cardiovascular, pulmonary and immunological disease.
结局指标
主要结局
Management of diabetic foot ulcers.
时间窗: one year
Assessment role of negative pressure wound therapy in treating diabetic foot ulcers.
次要结局
未报告次要终点
研究者
Abdelrahman Ibrahim Sayed
Vascular Surgery Department, Assiut University
Assiut University
