Comparative Outcomes of Dextrose Prolotherapy Versus Intra-articular Corticosteroid Injection in Patients with Osteoarthritis Knee, Randomized Controlled Trial

Phase 1

Completed

• Conditions: Osteoarthritis knee; Prolotherapy, steroid, intraarticular injection, osteoarthritis knee, VAS, WOMAC

• Registration Number: TCTR20230222002
• Lead Sponsor: Rajavithi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-12-31
• Study Start: 2023-02-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

patients age 45-75 years old, OA knee grade II-III, knee pain at least 3 months, visual analog scale (VAS) more or equal than 3

Exclusion Criteria

dextrose, xylocaine or steroid allergy, history of knee replacement surgery, pregnancy, on anti-coagulant therapy, intraarticular injection therapy in last 3 months, secondary osteoarthritis knee such as gouty arthritis, psoriatic arthritis or septic arthritis, external wound or abscess around the knee, unwilling to stop taking NSAIDs after treatment and platelet count < 100,000 cell/mm3

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual analog scale 24 week ask for pain score

Secondary Outcome Measures

Name	Time	Method
Western Ontario and McMaster osteoarthritis index 24 wk ask for quality of life