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Clinical Trials/NCT04584177
NCT04584177
Completed
Not Applicable

Arm-hand Boost Program During Inpatient Rehabilitation After Stroke: Pilot Randomized Controlled Trial

Jessa Hospital1 site in 1 country20 target enrollmentMay 9, 2019
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Jessa Hospital
Enrollment
20
Locations
1
Primary Endpoint
Change from Fugl-Meyer Assessment-Upper Extremity at 8 weeks
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

A pilot cross-over RCT including participants with sub-acute stroke is conducted in an inpatient rehabilitation setting. The experimental group (EG) receives an arm-hand boost program on top of their usual care program. The control group (CG) receives a dose-matched program of strengthening exercises for the lower limbs and general reconditioning. After 4 weeks, a cross-over is performed. Before, after 4 weeks and after 8 weeks of additional therapy, different clinical outcome measures for the upper limb are administered.

Registry
clinicaltrials.gov
Start Date
May 9, 2019
End Date
November 3, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Jessa Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • first stroke, as defined by WHO,
  • minimal stay of 4 weeks in inpatient setting at study start
  • minimally 18 years old
  • being able to sit independently (trunk control test, item 3 = 25),
  • motor impairment in the upper limb (Fugl-Meyer assessment, stage 2 (synergies): 8-17p, or stage 2: \<8p combined witht stage 5 (hand): \>6p
  • sufficient cooperation to perform intervention and evaluations

Exclusion Criteria

  • musculoskeletal and/or other neurological impairments with permanent damage that may hinder the study
  • subdural hematoma, tumor, encephalitis, trauma, or other that lead to similar symptoms as stroke
  • severe communication, cognitive or language impairments that hinder the investigations
  • no written informed consent

Outcomes

Primary Outcomes

Change from Fugl-Meyer Assessment-Upper Extremity at 8 weeks

Time Frame: Between baseline and end of study (=8 weeks)

UL assessment - Function

Change from Fugl-Meyer Assessment-Upper Extremity at 4 weeks

Time Frame: Between baseline and first 4 weeks of study

UL assessment - Function

Change from Action Research Arm Test at 4 weeks

Time Frame: Between baseline and first 4 weeks of study

UL Assessment - Activities

Change from Action Research Arm Test at 8 weeks

Time Frame: Between baseline and end of study (=8 weeks)

UL Assessment - Activities

Secondary Outcomes

  • Change from Box & Block test at 4 weeks(Between baseline and first 4 weeks of study)
  • Change from Jebsen Taylor hand function test at 8 weeks(Between baseline and end of study (=8 weeks))
  • Change from Rivermead Motor Assessment Arm function at 4 weeks(Between baseline and first 4 weeks of study)
  • Change from Rivermead Motor Assessment Arm function at 8 weeks(Between baseline and end of study (=8 weeks))
  • Change from Stroke upper limb capacity scale (SULCS) at 4 weeks(Between baseline and first 4 weeks of study)
  • Change from Stroke upper limb capacity scale (SULCS) at 8 weeks(Between baseline and end of study (=8 weeks))
  • Change from Jebsen Taylor hand function test at 4 weeks(Between baseline and first 4 weeks of study)
  • Change from Box & Block test at 8 weeks(Between baseline and end of study (=8 weeks))

Study Sites (1)

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