A randomized control study to see the effect of intensive treatment of hypertension and hyperlipidemia on patients having documented coronary artery disease.
- Conditions
- Patients diagnosed as having 75% or higher stenosis according to the AHA classification in at least one branch of the coronary artery with hypertension and hyperlipidemia.
- Registration Number
- JPRN-UMIN000000571
- Lead Sponsor
- J-CADII study committee
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 500
Not provided
Patients are excluded from study inclusion if they have 1) allergy to test drugs 2) familial hypercholesterolemia 3) uncontrolled hyperlipidemia (LDL-C >= 180mg/dL) 4) uncontrolled hypertension (systolic blood pressure >= 180mmHg and/or diastolic blood pressure >= 110mmHg) 5) AMI and/or stroke within 3months before intervention 6) secondary hypertension 7) secondary hyperlipidemia 8) severe valvular disease including mitral stenosis or incompetence of the aortic valve 9) severe arrhythmia including ventricular fibrillation or ventricular tachyrhythmia 10) renal failure (serum creatinine >=2.5 mg/dL) 11) liver dysfunction (AST and/or ALT over three times the normal value) 12) pregnancy and/or possibility of pregnancy or if the attending doctor disqaulifies the patients to be included in the study for whatever reason.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method