Comparison of toothpaste containing mango twig and market available toothpaste on oral bacteria and debris among 12-15 years old children in Davangere city.

Phase 2

Conditions: Health Condition 1: B999- Unspecified infectious disease

Registration Number: CTRI/2019/01/016897

Lead Sponsor: I

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1.Subjects whose parents will give consent for their children to participate in study.

2. Subjects having at least one cavitated active carious lesion

A cavitated active lesion â?? is a well-defined cavity with exposed dentin, yellowish or light brown in colour, which feels soft on gentle probing.

3. Having a streptococcus mutans count of equal to or more than 105 CFU per ml of saliva (microbiological selection criteria)

4.Subjects with a baseline mean plaque index score of at least 1.5 as determined by the use of the Turesky modification of the Quigley-Hein Plaque Index.

5. Subjects with presence of more than 20 scoreable teeth in the oral cavity

Exclusion Criteria

1. Subjects on medications and subjects with systemic diseases that affect their salivary flow rate.

2. History of hypersensitivity to any product used in the study

3. History of antibiotic therapy in the previous one month till the start of the study.

4. Subjects who will be unable to comply with the study appointment

Schedules

5. Subjects using orthodontic appliances

6. Subjects using adjunctive oral hygiene aid like mouthwash

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To assess and compare the antiplaque and antibacterial efficacy of Mangifera indica extract dentifrice, commercially available Fluoridated dentifrice (Colgate total care) and a Placebo dentifrice on salivary Streptococcus mutans levels and plaque levels among 12 â?? 15 years old school children in Davanagere cityTimepoint: 1.21 days after intervention

Secondary Outcome Measures