Comparison between Dexmedetomidine Versus Clonidine as Adjuvant to Ropivacaine in Ultrasound Guided Adductor canal block for Post-operative Analgesia in Lower Limb Orthopaedic Surgery: A Prospective Observational Study in a Tertiary Care Hospital in Mandya.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the duration of analgesia of clonidine and dexmedetomidine as adjuvant to 0.2% ropivacaine in adductor canal block
研究概览
简要总结
Various adjuvants have been added in peripheral nerve block to prolong the duration of analgesia. The present study is conducted to compare the clinical efficacy between Clonidine and Dexmedetomidine as adjuvants to Ropivacaine in ultrasound guided Adductor canal block in parameters of sensory blockade, duration of analgesia, number of rescue analgesia required in 24 hours and perioperative complications. The study is mainly conducted for post operative analgesia for patients undergoing elective lower limb orthopaedic surgeries. The adjuvants used in this study prolongs the duration of analgesia in the patients. Dexmedetomidine and clonidine are both having alpha 2 agonistic action and thus when added to a local anaesthetic like ropivacaine, have synergestic action.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of height 150-180 cm Weight 40- 80 kg Patient undergoing lower limb orthopaedic surgeries Patients with ASA PS grade 1 and
- •Patients willing to give informed consent.
排除标准
- •Patients having any local infection at site of insertion of needle.
- •patients having any known allergy to local anesthesia, peripheral neuropathy and coagulopathy.
结局指标
主要结局
To compare the duration of analgesia of clonidine and dexmedetomidine as adjuvant to 0.2% ropivacaine in adductor canal block
时间窗: To compare the adverse effects and the sedation scores between the groups upto a duration of 24 hours
To compare the intraoperative hemodynamic parameters between the groups.
时间窗: To compare the adverse effects and the sedation scores between the groups upto a duration of 24 hours
次要结局
- to compare the adverse effects and sedation scores between the groups(24 hours)
研究者
Dr Shivakumar G
Mandya Institute of Medical College Mandya