Ability of Cardio Q for Prediction of Hypotension

Completed

• Conditions: Prostate Cancer

• Registration Number: NCT03882697
• Lead Sponsor: Severance Hospital

Brief Summary

Evaluation the ability of each indicator of Cardio Q in predicting hypotension after position changes in robot-assisted laparoscopic radical prostatectomy

Detailed Description

Hypotension is common in patients who undergo general anesthesia. Hypotension may cause hypoperfusion in the organs of the body, resulting in ischemia and increased mortality within one year. Hypotension may occur at any time during general anesthesia but may also occur with changes in posture. In robot-assisted laparoscopic radical prostatectomy, hypotension often occurs when posture is changed from a Trendelenburg position to a supine position. However there is no data regarding which hemodynamic parameters can predict hypotension induced by position change.

Excessive administration of the fluid in steep Trendelenburg position may lead to fluid overload and lead to complications such as pulmonary edema. Thus, the predictors are should be identified to manage patients without fluid overload. Therefore, the aim of this study is to investigate the parameters of Cardio Q which are useful for predicting hypotension after position change.

Study Timeline

• Study Start: 2019-01-01
• Study First Submitted: 2019-02-12
• Study First Submitted QC: 2019-03-19
• Study First Posted: 2019-03-20
• Primary Completion: 2020-09-24
• Study Completion: 2020-09-24
• Status Verified: 2020-12
• Last Update Submitted: 2020-12-18
• Last Update Posted: 2020-12-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 125

Inclusion Criteria

Patients undergoing robot-assisted laparoscopic radical prostatectomy ASA 1-3

Exclusion Criteria

Patients that

• Unstable angina, left ventricular ejection fraction <40%
• Severe vascular disease
• Insertion type : pacemaker / defibrillator
• Autonomic nervous system diseases
• When esophageal varices are present
• If the subject includes a person who can not read the written consent (eg, illiterate, foreigner, etc.)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean arterial pressure	Before position change, After position change (1, 3, 5, 7, and 10 minutes)	The changes mean arterial pressure

Trial Locations

Locations (2)

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of

Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of