Prospective investigation of the Hypotension Prediction Index and other haemodynamic parameters using the HemoSphere system in patients undergoing fetoscopic surgery

Recruiting

• Conditions: O26.5; Maternal hypotension syndrome

• Registration Number: DRKS00033180
• Lead Sponsor: KGM - Klinik für Anästhesie und Intensivtherapie am Standort Marburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 10

Inclusion Criteria

Patients undergoing a foetoscopic procedure
- signed declaration of consent for inclusion in the examination

Exclusion Criteria

- Patients < 18 years of age
- Patients without already established invasive blood pressure measurement
- Patients who do not wish to participate in the examination (i.e. no signed consent form is available)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reliability of the Hypotension Prediction Index (HPI) to consider hypotension as probable before the event occurs (HPI value > 85%)

Secondary Outcome Measures

Name	Time	Method
- Mean arterial blood pressure (MAP)<br>- Eadyn (dynamic arterial elasticity)<br>- Stroke volume (SV), stroke volume variation (SVV), stroke volume index (SVI)<br>- Cardiac Output (CO), Cardiac Index (CI)<br>- Systemic vascular resistance (SVR), indexed systemic vascular resistance (SVRI)<br>- Maximum rate of intraventricular pressure rise (dP/dtmax)<br>- Serum lactate (blood gas analysis)<br>- Sum and type of infused volume (e.g. crystalloids, colloids)<br>- Sum and type of circulatory drugs used (e.g. noradrenaline, cafedrine/theoderenaline)