ANRS CO10 EPF - Cohort of HIV-infected Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 812
- 试验地点
- 23
- 主要终点
- Conditions of access to early treatment
研究概览
简要总结
The purpose of this study is to describe the conditions of access to early treatment of children infected with HIV, their management on the long-term, and impact on growth, clinical and immunovirological prognosis, adherence to treatment, living conditions
详细描述
The CO10 EPF paediatric cohort includes therapeutic, clinical and biological detailed questionnaires. The data are collected by the doctors every three months to 2 years and then every 6 months until to 18 years or every year by a simplified questionnaire if medical follow up continues outside of a participating site.
After 18 years of age, the patients are eligibile for the ANRS CO19-Coverte cohort.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HIV-infected children born to mothers included in ANRS-CO1 EPF or children under the age of 13 newly entered in care management with no prior antiretroviral therapy, whose mother was or not included in ANRS-CO1 EPF
排除标准
- •>= 13 years
- •refusal of legal representative of the child
- •antiretroviral therapy started before the entry in care management
- •care management for over 6 months before inclusion
结局指标
主要结局
Conditions of access to early treatment
时间窗: At inclusion and every six months up to 18 years
social factors (Geographical origin, living conditions, school level, age) and infection stage
次要结局
- Puberty stage(At 8 years and every six months up to 18 years)
- Sexuality(At 15 years and every six months up to 18 years)
- Immuno virological prognosis(At inclusion and every six months up to 18 years)
- Clinical prognosis(At inclusion and every six months up to 18 years)
- Prognosis of patient coinfected by CMV or VHC(At inclusion and every six months up to 18 years)