Intraoperative Hyperglycemia and Infections After Orthopedic Surgery

• Conditions: Severe Hyperglycemia; Postoperative Infection; Orthopedic Patients

• Registration Number: NCT03903354
• Lead Sponsor: Federico Bilotta

Brief Summary

Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy. The aim of this study is to evaluate the epidemiology of intraoperative severe hyperglycemia (BGC \>180 mg/dL; 10 mmol/L) and postoperative infections (wound, urinary and prosthetic joint infection) and to investigate if severe intraoperative hyperglycemia is associated with an higher risk of early postoperative (within the 7th postoperative days) infections (wound, urinary and prosthetic joint infection).

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-13
• Primary Completion: 2018-04-13
• Status Verified: 2019-04
• Study First Submitted: 2019-04-02
• Study First Submitted QC: 2019-04-02
• Last Update Submitted: 2019-04-03
• Study First Posted: 2019-04-04
• Last Update Posted: 2019-04-05
• Study Completion: 2019-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Orthopedic patients

Exclusion Criteria

• Non-orthopedic patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severe hyperglycemia and incidence of infection	Follow up of the patients for 7 days postoperatively	Evaluate the relationship between intraoperative severe hyperglycemia and incidence of infections at 7 days follow up.

Trial Locations

Locations (1)

Sapienza; 🇮🇹 Roma, RM, Italy