Comparison of the Efficiency of Tissue Adhesive (Periacryl 90) and Silk Suture in Mandibular Impacted Wisdom Surgery

Not Applicable

Completed

• Conditions: Impacted Mandibular Third Molar Extraction

• Registration Number: NCT06811974
• Lead Sponsor: Yuzuncu Yıl University

Brief Summary

In this study, bilateral It is aimed to compare the efficacy of tissue adhesive (Periacryl 90) and silk suture in mandibular impacted wisdom tooth surgery.

Detailed Description

In the study carried out on a total of 30 patients, 21 females and 9 males, 60 fully impacted lower wisdom teeth were extracted bilaterally and in the same position. One of the bilateral bilateral teeth of the patients was randomly selected and tissue adhesive (Periacryl 90) was applied for wound closure as the experimental group, while the other tooth was determined as the control group and the wound was closed with silk suture. The selected party was determined by the closed envelope method. After the first impacted tooth was extracted, it was waited until the wound healed and the symptoms disappeared completely, then the other tooth was extracted. In both tooth extractions, wound healing, edema and trismus were evaluated on the 3rd and 7th days. Wound healing was evaluated as good, acceptable and bad. VAS (Visual Analog Scale) was used for pain assessment and assessment was made at 3, 6, 12 and 24 hours and 2, 3, 4, 5, 6 and 7 days.

Study Timeline

• Study Start: 2022-05-01
• Primary Completion: 2023-04-30
• Study Completion: 2024-04-30
• Study First Submitted: 2025-01-24
• Study First Submitted QC: 2025-01-31
• Status Verified: 2025-02
• Study First Posted: 2025-02-06
• Last Update Submitted: 2025-02-06
• Last Update Posted: 2025-02-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Healthy individuals aged 18-35 years who accepted the study conditions and had bilateral, bone or mucosal retention, and completely impacted wisdom teeth in the similar position with an indication for extraction due to prophylactic or orthodontic treatment in the lower jaw were included in the study.

Exclusion Criteria

• Individuals with any systemic disease
• Individuals with a history of allergy to the drugs to be used in the study
• Pregnant and breastfeeding individuals
• Individuals with pain, swelling or trismus in the last 10 days
• Individuals with different positions on the right and left sides
• Individuals who did not sign the voluntary consent form
• Individuals with pathology in the impacted tooth area
• Individuals with limited mouth opening

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Wound Healing	3. and 7. days	All patients were called for follow-up visits on the 3rd day and 1 week later and were examined by the same physician. During the follow-up visits, the status of wound healing was evaluated in 3 different statuses. These 3 statuses were recorded as good, acceptable and poor. Wound healing deteriorated from good to poor.
Edema	3. and 7. days	In order to evaluate edema, the distances between points marked extra orally in 5 different regions on the face were measured and recorded in mm (angulus-tragus point, angulus-lateral corner of the eye, angulus-nasal wing, angulus-lateral commissure, angulus-pogonion point).
Trismus	3. and 7. days	The evaluation of trismus was evaluated by measuring the mouth opening before the operation and also on the 3rd and 7th days after the operation. The patients were asked to open their mouths as much as possible and the distance between the incisal edges of the lower and upper central incisors was measured in millimeters with the help of a precision ruler. This process was repeated 3 times for each measurement and the arithmetic average of the values found was taken.
VAS Pain Scor	3, 6, 12 and 24 hours and 2, 3, 4, 5, 6 and 7 days.	VAS (Visual Analog Scale) was used for pain assessment. VAS pain assessment includes scores between 0 and 10. (0: no pain; 10: unbearable pain.) As the score increases, the pain worsens.

Trial Locations

Locations (1)

Van Yüzüncü Yıl Üniversitesi Diş Hekimliği Fakültesi; 🇹🇷 Van, Turkey