Do Treatment Interventions for Obstructive Sleep Apnoea Reduce Depressive Symptoms in Patients with Comorbid Depression?

Not Applicable

Completed

• Conditions: Obstructive Sleep Apnoea; Depression; Respiratory - Sleep apnoea; Mental Health - Depression

• Registration Number: ACTRN12614000013662
• Lead Sponsor: Royal Melbourne Institute of Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-06
• Study Completion: 2019-01-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

Untreated OSA patients who have been recommended to start CPAP therapy; English fluency; not pregnant or possibility of being pregnant; CES-D score >16. Patients with a current clinical diagnosis of depression, and who are on antidepressants will also be included.

Exclusion Criteria

History of or current psychiatric or medical condition (except depression) including epilepsy, recent stroke, myocardial infarction (in last 6 months); excessive daytime sleepiness (ESS>16); head injury with loss of consciousness >15 mins; learning disability; alcohol or drug dependence; shiftwork; and any neurological disorder or inability to complete the trial at the judgment of the clinician investigator.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression score - (Center for Epidemiology - Depression scale)[1, 2, 4 and 12 months];Daytime Sleepiness (Epworth Sleepiness Scale (ESS)[1, 2, 4 and 12 months]

Secondary Outcome Measures

Name	Time	Method
Emotional Reactivity Scale and Difficulties in Emotional Regulation Scale[1, 2, 4, 12 months]