Continuous Positive Airway Pressure (CPAP) for the treatment of severe respiratory distress in the pre-hospital setting

Phase 3

Completed

• Conditions: Severe respiratory distress.; Heart failure; Respiratory - Other respiratory disorders / diseases; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12615001180505
• Lead Sponsor: Curtin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-03
• Study Completion: 2019-06-30
• Last Update Posted: 2 May 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 708

Inclusion Criteria

Age 40 plus years, transported to a metropolitan hospital by ambulance, respiratory rate > 22 breaths per minute and identified by paramedics as experiencing severe respiratory distress of non-traumatic origin which is deteriorating despite 5 minutes of appropriate therapy

Exclusion Criteria

Excluded if immediate endotracheal intubation or other methods of airway control, e.g. laryngeal mask airway are required; unconscious or only responds to pain; systolic blood pressure <90mmHg; uncooperative patient; possible pneumothorax, anaphylaxis, drowning, smoke inhalation, or aspiration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in respiratory rate assessed by paramedics, as indicated on electronic patient care record (e-PCR)[Paramedic arrival within 5 minutes at the prehospital scene to immediately prior to arrival to the emergency department];Changes in the VAS dyspnoea score measured by a Visual Analogue Scale that patients rate their difficulty in breathing from 1 (no shortness of breath) to 10 (worst difficulty in breathing imaginable)[Paramedic arrival within 5 minutes at the prehospital scene to immediately prior to arrival to the emergency department];Duration of hospital length of stay (LOS) (days) - as determined by hospital records[Length of stay will be calculated in days. after discharge from hospital]