3d computed tomography analysis of arytenoid adduction in patients with unilateral vocal fold paralysis.

Recruiting

• Conditions: Unilateral vocal fold paralysis; 10019190

• Registration Number: NL-OMON54444
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- Adult >18 years old
- Unilateral vocal fold paralysis diagnosed by experienced ENT-surgeon
- To be able and willing of giving informed consent
- Indicated to undergo laryngeal framework surgery: medialization + arytenoid
adduction

Exclusion Criteria

- Previous laryngeal framework surgery
- Laryngeal injection augmentation less than 3 months before LFS
- Patients with active head and neck malignancy
- Patients with contra-indication for CT-scan

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary Objective: CT scan pre-operative and postoperative will give<br /><br>information about:<br /><br>- Change in the position of the arytenoid cartilage </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary Objective(s):<br /><br>These objectives are obtained from standard practice of care & follow up:<br /><br>- Perceptive voice analysis: Grade of the GRBAS score system<br /><br>- Visual analysis: videolaryngostroboscopy<br /><br>- Acoustic voice analysis: S/Z ratio, Speech phonetogram with extremes of<br /><br>dynamic range(dB) and melodic range(ST), Fundamental frequency (Hz)<br /><br>- Aerodynamic / efficiency voice analysis: maximum phonation time (sec)<br /><br>- Subjective rating by patient: PROMS (VHI-30 questionnaire and numeric scale)</p><br>