The effect of vitamin A on intestinal mucosal injury in pediatric patients receiving hematopoietic stem cell transplantation and chemotherapy: a randomized controlled clinical trial

Not Applicable

Completed

• Conditions: vitamin A insufficiency in pediatric hematopoietic stem cell transplant patients; hematopoietic stem cell transplantation, vitamin A supplementation, citrulline, mucosal injury, pediatrics

• Registration Number: TCTR20191207002
• Lead Sponsor: Ramathibodi hospital reserach grant

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-08-31
• Study Start: 2019-12-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

patients age 1-18 years who underwent hematopoietic stem cell transplantation during May 2017 to August 2018 at the Bone marrow transplantation unit, Ramathibodi hospital, Thailand

Exclusion Criteria

patients received vitamin A supplementation in the previous three months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
change in plasma citrulline after vitamin A supplementation and hematopietic stem cell transplant baseline, day 0 and day 7 after stem cell infusion plasma citrulline

Secondary Outcome Measures

Name	Time	Method
post transplant complication and clinical of vitamin A toxicity 60 days after transplantation outcome of patients