Study on the Role of Senescence and Neurodegenerative Biomarkers in Major Depressive Disorder subject during Escitalopram treatment
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 65
- 试验地点
- 1
研究概览
简要总结
This study is a non-randomized single arm observational follow up study in which 65 subjects diagnosed with Major Depressive Disorder (single episode / recurrent) prescribed for Escitalopram treatment (10 mg OD, Oral) will be recruited. The participants will be recruited based on the inclusion and exclusion criteria. The study will be conducted at MGM School of Biomedical Sciences, Navi Mumbai. The study has been approved by the Institutional Ethics Committee. Informed consent will be obtained from each participant and their legal representative or family member. The blood samples of the study participants will be evaluated for the levels of senescence and neurodegeneration biomarkers at Baseline (before treatment starts), 3 months interval and 6 months interval. The results obtained for 3 months and 6 months will be compared with the results of baseline data for interpretation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- All
入选标准
- •Individuals diagnosed with Major Depressive Disorder based on structured clinical questionnaire as per DSM 5 criteria (American Psychiatric Association, 2013) and prescribed for Escitalopram treatment by Psychiatrists will be included in the study.
- •Individuals of both sexes in the age group of 18 to 35 years will be included.
- •Individuals willing to participate in the study will be included.
排除标准
- •Individuals suffering from Head injury, cerebral stroke, dementia, chronic diabetes, poisoning, schizophrenia, chronic alcoholism or any other severe mental illness and disease affecting brain except Depression will be excluded from the study.
- •The individuals not willing to participate in the study were excluded from the study.
- •Individuals having the last 2 months history of drug treatment with significant central serotonergic effects or any investigational treatment for MDD will be excluded from the study.
研究者
Dr Neelam Yeram
MGM School of Biomedical Sciences, Navi Mumbai