Study on the safety of thiopurine preparations during pregnancy
Not Applicable
Recruiting
- Conditions
- All diseases for which thiopurine preparations are used
- Registration Number
- JPRN-UMIN000045148
- Lead Sponsor
- Tohoku University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
Not provided
Exclusion Criteria
Cases in which the medication status at the time of pregnancy cannot be determined. Cases in which all the specimens of the partner (required) and the child (required for children born in pregnancies while taking thiopurine, optional for other pregnancies) are not available.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of NUDT15 genotype in infants for each NUDT15 genotype pair of parents
- Secondary Outcome Measures
Name Time Method Frequency of pregnancy complications, frequency of genetic mutations in children, and analysis of transmission disequilibrium in pregnancies taking thiopurine