CTRI/2025/03/082570Not yet recruitingPhase 2
A comparative evaluation of two different doses of Dexmedetomidine in producing controlled hypotension during Functional endoscopic sinus surgery
DR Mehjebin Ahmed1 site in 1 country45 target enrollmentStarted: March 29, 2025Last updated:
Trial Snapshot
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- to evaluate and compare the following factor in two different dose group for dexmedetomidine-
Study Overview
Brief Summary
Functional endoscopic sinus surgery is a surgery of sinus included bleeding in surgical field. by using dexmedetomidine to induce hypotension causes less surgical field bleeding. to find out the appropriate dose of dexmedetomidine during intraoperative period among two different dose.
Study Design
- Study Type
- Interventional
- Allocation
- Other
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 50.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients of all sex Elective FESS surgeries aged from 18 years to 50 years.
- •Patients with ASA Grade I and II physical status.
Exclusion Criteria
- •â€¢ Patient refusal • Pregnancy • Any known allergic condition or contraindication to GA, • Hypertensive patient undergoing antihypertensive medication • Any cardio vascular, renal disease.
Outcomes
Primary Outcomes
to evaluate and compare the following factor in two different dose group for dexmedetomidine-
Time Frame: Time taken to induce hypotension
1.mean arterial pressure
Time Frame: Time taken to induce hypotension
2. heart rate variability
Time Frame: Time taken to induce hypotension
3. bleeding
Time Frame: Time taken to induce hypotension
4. time taken to induce hypotension
Time Frame: Time taken to induce hypotension
Secondary Outcomes
- amount of bleeding(intraoperative)
Investigators
DR.Mehjebin Ahmed
Silchar Medical College and Hospital
Study Sites (1)
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