NCT05187871Unknown不适用
Establishment and Research for Rapid Diagnosis of Postoperative Abdominal Infection Based on Metagenomic Sequencing
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The pathogenic spectrum of postoperative abdominal infection
研究概览
简要总结
This is a prospective and exploratory study, which utilizes non-targeted metagenomic next-generation sequencing (mNGS) detecting drain fluid from patients who are suspected of postoperative abdominal infection. This study aims to explore the clinical value of mNGS in the rapid diagnosis of postoperative abdominal infection, to refine the pathogenic bacteria spectrum, and to establish a novel procedure for postoperative abdominal infection diagnosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who receive abdominal operations with routinely abdominal drainage placement.
- •Abdominal infection is suspected by the clinicians, and one of the following conditions is met:
- •Temperature ≥38℃;
- •One of the following laboratory indicators: WBC≥10×10^9/L, PCT≥0.5ng/ml, hsCRP≥100mg/L.
排除标准
- •Patients who are diagnosed with the abdominal infection before surgery.
- •Evidence of non-abdominal infection is clear and could explain the clinical symptoms.
结局指标
主要结局
The pathogenic spectrum of postoperative abdominal infection
时间窗: Through study completion, an average of 1 year
次要结局
- Consistency between mNGS and conventional culture methods(Through study completion, an average of 1 year)
研究者
研究点 (1)
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