NCT00876629CompletedNot Applicable
Renal MR Elastography: Normal Findings and Variability of Stiffness Measurements
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Hospices Civils de Lyon
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Variability of stiffness measurement (on repeat examination)
Study Overview
Brief Summary
MR Elastography is a new technique aimed at non-invasively measuring the stiffness of tissues. It has recently given interesting results in the assessment of liver fibrosis.
The objectives of the current study are:
- to develop an imaging protocol for MR Elastography of the kidneys;
- To calculate the stiffness of normal kidneys;
- To evaluate the variability of the measurements of kidney stiffness by repeating the procedure twice on the same volunteers.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age between 18 and 40
- •Signed informed consent form
- •Insured by the French Social Security
Exclusion Criteria
- •Pregnancy
- •Personal or familial history of kidney disease
- •Hypertension
- •Contraindication to MRI
Outcomes
Primary Outcomes
Variability of stiffness measurement (on repeat examination)
Time Frame: 2 months
Normal kidney stiffness (measured from MRE data)
Time Frame: 2 months
Secondary Outcomes
- Percentage of partial and total technical failures(2 months)
- Tolerance of the procedure(2 months)
- Quality criteria of stiffness measurements (area of the ROIs used for measurement, mean induced displacement measured in the ROIs)(2 months)
Investigators
Study Sites (1)
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