NCT00953784已完成不适用
Minimization of Surgical Site Infections for Pts Undergoing Colorectal Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 197
- 试验地点
- 2
- 主要终点
- %/type Surgical wound infections rated per infection classifications of NNIS/CDC
研究概览
简要总结
This is a comparison, at this VA Hospital, of standard operating room management in colorectal surgery to a more rigid management using an additional five previously tested treatments to determine if this changes the rate of post operative wound infections.
详细描述
A comparison between standard operating room:
- use of pre-op bowel prep (Golytely or Phosphosoda,plus 3 doses of oral antibiotics(Erythromycin and Neomycin), and fleets enema the day before surgery
- Standard anesthesia FiO2 (approx. 30-50%)during surgery
- Standard IV fluids during surgery(greater than 200cc per hour)
- Standard post-op O2 by mask for 2 hours
To extended operating room procedures of:
- No po antibiotics or pre-op bowel prep other than enema prior to surgery
- Skin warming at least 15 minutes prior to and during surgery(core temp 36C+)
- IOBAN drapes and Plastic wound protectors used during surgery
- Restricted IV fluids less than 200cc per hour during surgery
- Increased FiO2 to 80% during surgery and 2 hours after by mask
Monitoring for post-op wound infections at discharge and up to 30days post-op
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled VA adult elective colorectal surgery patient
排除标准
- •Non VA adults, emergent colorectal surgery, scheduled multiple surgery procedures,pts with other infections being treated
结局指标
主要结局
%/type Surgical wound infections rated per infection classifications of NNIS/CDC
时间窗: with in 30 days post-op
次要结局
- %/type surgical wound infections per classifications per NNIS/CDC(at hospital discharge)
研究者
研究点 (2)
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