evaluation of two doses of Etoricoxib (90mg and 120mg) as pre-operative preemptive analgesic for postoperative pain relief in mandibular fracture surgery
Phase 3
Completed
- Conditions
- Health Condition 1: null- Mandibular Fracture
- Registration Number
- CTRI/2017/08/009272
- Lead Sponsor
- All India Institute Of Medical Sciences New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
60 adult patients of 18 to 50 yrs age group, ASA grade I-II under going mandibular fracture surgery
Exclusion Criteria
1.Known allergy, sensitivity, contraindication to Etoricoxib/NSAID
2.Patient with hypertension, asthma, bleeding disorders
3.Patient on anticoagulants
4.History of dyspepsia, pain abdomen, peptic ulcer
5.Patient with Coronary artery and peripheral vascular disease
6.Patient with cerebrovascular disorder
7.Patient with hepatic and renal impairment
8.Already on analgesics for control of pain for some other ailment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the efficacy of oral Etoricoxib90mg and 120mg, as a pre-emptive analgesicin post operative analgesia as compared to placebo following open reduction internal fixation of mandibular fracture.Timepoint: The data will be recorded at every 1hr for the first 4 hours there after at 8th,12th and 24th hr
- Secondary Outcome Measures
Name Time Method Compare patient satisfaction and side effects to EtoricoxibTimepoint: 4hrs, 8th, 12th 24 hr