Effect of Periodontal Intervention on Oxidative Stress in Chronic Kidney Disease Patients suffering from Moderate to Severe Periodontitis

Suhani Maheshwari0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Age range: 30-60 years
•Chronic Kidney Disease
•Patients suffering from moderate to severe periodontitis
•Non-smoking (former smokers were included if they had not smoked within 6 months of the study initiation)
•No periodontal therapy within previous 6 months.
•Patients who give consent
•Patients with minimum 20 teeth

•History of atherosclerosis involving the coronary cerebral or peripheral vascular systems
•Experiencing a cardiovascular event (myocardial infarction or stroke) or undergoing coronary angioplasty or peripheral intervention procedure between the Screening Visit and randomization
•Undergoing any cardiovascular surgery (valvular surgery) within 3 months of study participationPlanned revascularization or peripheral intervention procedure or other cardiovascular surgery
•New York Heart Association (NYHA) Class III or IV heart failure at study participation
•Patient of End stage renal disease (ESRD)/ patients on hemodialysis or peritoneal dialysis
•Patients chronically treated (i.e 2 week or more) with any medication that affect periodontal status (i.e antibiotics or non-steroidal anti-inflammatory drugs) or lipid peroxidation with clinically significant or unstable organic diseases or compromised healing potential (i.e. connective tissue disorders or bone metabolic diseases).
•Pregnant women or lactating.
•Patients affected by active infectious diseases Asthma Diabetes Immune-compromised or taking steroid medications.

发起方

Suhani Maheshwari