Yoga for lung functions in COVID-19 survivors

Phase 2

Not yet recruiting

• Conditions: Coronavirus as the cause of diseases classified elsewhere,

• Registration Number: CTRI/2021/09/036829
• Lead Sponsor: All India Institute of Medical Sciences

Brief Summary

Coronavirus disease recovered cases reveal the varying degrees of radiological abnormalities associated with the deterioration of the pulmonary function which could manifest in a cascade of cardiopulmonary consequences and abnormal lung function. Also, unprecedented change, fear, and uncertainty during the COVID era has implicated in emotional distress, psychosocial dysfunction, and a surge of mental health problems. Yoga improvement in pulmonary function, rehabilitation, Health-Related Quality of Life and reduces Anxiety & Depression, several types of research have demonstrated the benefits of yoga. The current study attempts to explore yoga-based rehabilitation using a validated and customized yoga module. Keeping this in consideration, a randomized controlled open-label, endpoint blind, a clinical trial is planned to evaluate Yoga therapy as an add-on to standard care in Post covid patients.The proposed study design is a prospective randomized open label blinded endpoint trial with 1:1 allocation ratio. The study participant may fall into the intervention arm will give Yoga for 30 mint for 12 weeks.outcome measures on Baseline, after 6 weeks and at the end of 12 weeks of study.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-09-22
• Study Start: 2021-11-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 104

Inclusion Criteria

a)Known case of COVID patients with respiratory symptoms on screening (RT-PCR negative or 4 weeks to 8 weeks from the onset of first symptom) b)Patients with forced vital capacity(FVC)<80% c)Patients of both sex and age of18-75years d)Patients who are able and willing to practice any form of exercise when recruited under the study e)Patients who are not engaged in regular and structured yoga practice.

Exclusion Criteria

• a)Patients with forced vital capacity FVC<40 % b)Previous pulmonary complications like severe asthma, COPD, bronchiectasis, interstitial lung disease(IL) c)Known cases of CAD with moderate to severe LV dysfunction, patients with a history of CV or neurodegenerative diseases.
• d)Lactating and pregnant women.
• e)Patients currently participating in any other clinical trials with intervention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pulmonary Function: Diffusion lung capacity for carbon monoxide (DLCO), Forced Vital capacity (FVC), Forced expiratory volume in first second (FEV1), Total lung capacity (TLC) using Pulmonary function test	Baseline, after 6 weeks and at the end of 12 weeks

Secondary Outcome Measures

Name	Time	Method
Severity of dyspnea using UCSD Shortness of Breath Questionnaire.	Exercise capacity using 6-minute walk test

Trial Locations

Locations (1)

All India Institute of Medical Science; 🇮🇳 Delhi, DELHI, India

All India Institute of Medical Science

🇮🇳Delhi, DELHI, India

Dr Randeep Guleria

Principal investigator

9911110487

randeepguleria2002@yahoo.com