The effect of platelet-rich fibrin on neurosensory recovery of inferior alveolar nerve injury

Not Applicable

Conditions: Inferior Alveolar nerve neurosensory defect due to mandibular body fracture.
Injury of trigeminal nerve
S04.3

Registration Number: IRCT20200922048799N2

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 13

Inclusion Criteria

The patients with bilateral mandibular body fracture with less than 5mm displacement, who are candidates for open reduction-internal fixation (ORIF)

Exclusion Criteria

Patients with other types of fracture or those who are not a candidate for the ORIF treatment method
History of mandible genioplasty or orthognathic surgery
History of mandible trauma
History of mandibular fracture
Obvious perioperative nerve injury
Psychiatric medication
Refusing to participate in the postoperative examinations
Having neuropathic systemic diseases such as diabetes
Having no consent for participation in the study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The two-point discrimination test (TPD). Timepoint: before the surgery (T0), 6 months after the surgery (T1), and 12 months after the surgery (T2). Method of measurement: the minimum distance of two discriminable points, which is created by a needle on the lower lip and the mental area.;The brush directional stroke discrimination test. Timepoint: before the surgery (T0), 6 months after the surgery (T1), and 12 months after the surgery (T2). Method of measurement: performed by movement of a thin brush on the lower lip and the mental area and the patient must recognize the direction of the brush movement.;Self reported paresthesia. Timepoint: before the surgery (T0), 6 months after the surgery (T1), and 12 months after the surgery (T2). Method of measurement: using the visual analogue scale with a score range of (1-10) so that scores of (1 to 3), (4 to 6), and (7-10) are defined as mild, moderate, and severe, respectively.

Secondary Outcome Measures