Hypopituitarism in patients after subarachnoid hemorrhage: Screening and treatment.
Recruiting
- Conditions
- Hypopituitarism in patients after subarachnoid hemorrhage
- Registration Number
- NL-OMON23702
- Lead Sponsor
- erasmus medical centre
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
1. Subarachnoid hemorrhage;
2. Signed and dated informed consent document.
Exclusion Criteria
Subjects with any of the following items will be excluded from the study:
1. Any hypothalamic/pituitary disease diagnosed prior to SAH;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To determine the prevalence of hypopituitarism in patients after SAH;<br /><br>2. To identify neurological parameters that predict hypopituitarism after SAH;<br /><br>3. To determine the value of a Ghrelin test shortly after SAH, to identify subjects with GHD.<br>
- Secondary Outcome Measures
Name Time Method 1. To determine the impact of hypopituitarism on physical functioning, activity pattern and participation;<br /><br>2. To evaluate the effect of GH replacement on residual functional physical fitness, fatigue and quality of life.<br>