Cohort for biomarkers to predict prognosis and treatment response in acute leukemia
- Conditions
- Diseases of the blood and blood -forming organs and certain disorders involving the immune mechanism
- Registration Number
- KCT0002261
- Lead Sponsor
- The Catholic University of Korea, Seoul St. Mary's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1500
1) patient group
? step 1: adult with over 18-year-old, patients who confirmed of acute leukemia by WHO classification, patients who can be checked the electronic medical record
? step 2: adult with over 18-year-old, patients who suspected of acute leukemiaL, and then confirmed with bone marrow apsirate by WHO classification, Patients with voluntary informed consent about blood and bone marrow sampling.
2) healthy donor group
: among the all hematopoietic stem cell donors, healthy donor who donated with bone marrow cells
patients who not finally confirmed of acute leukemia by WHO classification
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Characteristics of patient and leukemia at diagnosis, type of chemotherapy, chemotherapy response, hematopoietic stem cell transplantation and related-survival rate, incidence of HSCT-related complications
- Secondary Outcome Measures
Name Time Method Promising biomarker determination