SUPPLEMENTARY EFFECTS OF RESISTANCE TRAINING IN ADDITION TO JOINT MOBILIZATION IN PERSONS WITH KNEE OSTEOARTHRITIS

Not Applicable

• Conditions: Knee Osteoarthritis
• Interventions: Procedure: Joint Mobilization; Device: Transcutaneous Electric Nerve Stimulation (TENS); Procedure: Resistance Exercise Training; Device: Heating Pad

• Registration Number: NCT06444932
• Lead Sponsor: Foundation University Islamabad

Brief Summary

Joint mobilization and resistance exercise training are effective conservative treatment options for the management of osteoarthritis. However, currently no study has highlighted the supplementary effects of resistance training in addition to joint mobilization in people suffering from knee osteoarthritis. The current study is aimed at bridging the gap in literature and providing evidence regarding the additive impact of resistance training to joint mobilization in knee osteoarthritis.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-05-27
• Status Verified: 2024-06
• Study First Submitted QC: 2024-06-05
• Last Update Submitted: 2024-06-05
• Study First Posted: 2024-06-06
• Last Update Posted: 2024-06-06
• Study Start: 2024-06-10
• Primary Completion: 2024-12-10
• Study Completion: 2024-12-30

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Knee OA grade I-III
• Individuals of either gender aged 40-70 years
• Knee OA history of no less than 3 months
• Knee pain no more than 8/10 cm on the visual analogue scale (VAS)
• Radiological evidence of grade III or less on Kellgren classification.

Exclusion Criteria

• Those with signs of serious pathology such as malignancy, inflammatory disorder or infection.
• History of trauma or fractures in lower extremity
• Signs of lumbar radiculopathy or myelopathy
• History of knee surgery or replacement and/or receiving intra-articular steroid therapy in the preceding two months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Active Comparator	Transcutaneous Electric Nerve Stimulation (TENS)	-
Experimental Group	Resistance Exercise Training	-
Active Comparator	Heating Pad	-
Experimental Group	Transcutaneous Electric Nerve Stimulation (TENS)	-
Experimental Group	Joint Mobilization	-
Experimental Group	Heating Pad	-
Active Comparator	Joint Mobilization	-

Primary Outcome Measures

Name	Time	Method
Gait velocity	4 weeks	Gait analysis will be done to analyze gaot velocity. A greater gait velocity signifies positive outcome and prognosis.
Walking related performance fatigability	4 weeks	Walking related performance fatigability will be measured using 6 minute walk test. Greater fatigability indicates poorer outcome.
Stride Length	4 weeks	Gait analysis will be done to analyze stride length. A greater stride length signifies positive outcome and prognosis.
Knee Pain	4 weeks	Knee Pain will be measured using visual analogue scale (VAS) from 0-100mm. A higher score on VAS indicated greater pain.
Knee range of motion	4 weeks	Knee range of motion will be measured using a goniometer. A higher ROM signifies positive outcome.
Isometric Muscle Strength	4 weeks	Isometric Muscle Strength will be quantified using dynamometer. A higher score on dynamometer signifies greater muscle strength and good prognosis.
Functional Disability	4 weeks	Knee functional disability will be assessed using Knee Osteoarthritis and Outcome Score (KOOS) with a score ranging from 0-100. A lower score on KOOS signifies greater functional disability.
Functional capacity	4 weeks	5 repetition sit to stand test will be used to determine knee related functional capacity, which will be quantified in terms of time. A smaller time will denote greater functional capacity.

Trial Locations

Locations (1)

Foundation Univeristy Islamabad; 🇵🇰 Islamabad, Pakistan