The Optimal Timing of Carbon Dioxide Insufflation During Colonoscopy in Unsedated Patients
Not Applicable
Completed
- Conditions
- Outpatients
- Registration Number
- NCT01415076
- Lead Sponsor
- Tri-Service General Hospital
- Brief Summary
Insufflation of carbon dioxide (CO2) instead of air can reduce pain resulting from colon distension after colonoscopy because CO2 is rapidly absorbed from the colon and excreted through the lungs. This reduces the effects of colonic distension and minimizes intracolonic gas at the end of the examination. The aims of the study were to evaluate the timing of administering CO2 insufflation and to identify predictors of discomfort for colonoscopy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- patients with an appropriate indication for colonoscopy were considered eligible.
Exclusion Criteria
- Exclusion criteria included severe hematochezia, acute colonic pseudo-obstruction, known obstructive lesions, age <18 years, prior colon resection, fulminant colitis, chronic obstructive pulmonary disease requiring oxygen, and a medical history of CO2 retention. Patients that required only a partial colonoscopy or were unable to read or understand Chinese were also excluded.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method abdominal pain during and after colonoscopy One day Pain was recorded on a ten-point visual analog scale (0- no pain, 10- worst imaginable pain) at left-sided colonoscopic insertion, right-sided colonoscopic insertion, and at 1, 3, 6, and 24 hours postprocedure.
- Secondary Outcome Measures
Name Time Method delayed bleeding One day colonoscopic cecal intubation time One day completeness of intubation One day loop formation One day
Trial Locations
- Locations (1)
Division of Gastroenterology, Tri-Service General Hospital
🇨🇳Taipei, Taiwan
Division of Gastroenterology, Tri-Service General Hospital🇨🇳Taipei, Taiwan