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The Optimal Timing of Carbon Dioxide Insufflation During Colonoscopy in Unsedated Patients

Not Applicable
Completed
Conditions
Outpatients
Registration Number
NCT01415076
Lead Sponsor
Tri-Service General Hospital
Brief Summary

Insufflation of carbon dioxide (CO2) instead of air can reduce pain resulting from colon distension after colonoscopy because CO2 is rapidly absorbed from the colon and excreted through the lungs. This reduces the effects of colonic distension and minimizes intracolonic gas at the end of the examination. The aims of the study were to evaluate the timing of administering CO2 insufflation and to identify predictors of discomfort for colonoscopy.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
200
Inclusion Criteria
  • patients with an appropriate indication for colonoscopy were considered eligible.
Exclusion Criteria
  • Exclusion criteria included severe hematochezia, acute colonic pseudo-obstruction, known obstructive lesions, age <18 years, prior colon resection, fulminant colitis, chronic obstructive pulmonary disease requiring oxygen, and a medical history of CO2 retention. Patients that required only a partial colonoscopy or were unable to read or understand Chinese were also excluded.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
abdominal pain during and after colonoscopyOne day

Pain was recorded on a ten-point visual analog scale (0- no pain, 10- worst imaginable pain) at left-sided colonoscopic insertion, right-sided colonoscopic insertion, and at 1, 3, 6, and 24 hours postprocedure.

Secondary Outcome Measures
NameTimeMethod
delayed bleedingOne day
colonoscopic cecal intubation timeOne day
completeness of intubationOne day
loop formationOne day

Trial Locations

Locations (1)

Division of Gastroenterology, Tri-Service General Hospital

🇨🇳

Taipei, Taiwan

Division of Gastroenterology, Tri-Service General Hospital
🇨🇳Taipei, Taiwan

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