3D Sonographic Measurement of Volumetric Flow in Transjugular Intrahepatic Porto-Systemic Shunts
- Conditions
- Liver DiseasePortal Hypertension
- Registration Number
- NCT02046473
- Lead Sponsor
- University of Michigan
- Brief Summary
To determine if ultrasound measurements can accurately measure the blood pressure of flow across a stent that has been placed in a portal vein to reduce portal vein pressure known as Transjugular Intrahepatic Porto-Systemic shunts or TIPS.
- Detailed Description
To determine if 3D ultrasound measurements can accurately measure the pressure of blood flow across a stent that has been placed in a portal vein. This has been done in order to reduce portal vein pressure. These shunts are known as Transjugular Intrahepatic Porto-Systemic shunts or TIPS.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
- Male and female 18 years of age and older
- Have an existing TIPS (Transjugular intrahepatic porto-systemic shunt)
- Have an ultrasound ordered by your physician to evaluate your TIPS.
- Able to read, understand and sign informed consent
- Under 18 years of age
- Cannot be pregnant
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Estimate portal blood flow within a transjugular portosystemic shunt 4 years To determine the number of volumes to achieve a specified variance in the measurement and to determine the reproducibility of the volume flow measurements taken at multiple locations within the stent (3 locations with 3 measurements each for a total of 9 acquisitions).
The physicians will measure volume flow rate three times at three different locations in the shunt (that being proximal, medial and distal) to determine the reproducibility of the flow estimate.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Michigan Hospital
🇺🇸Ann Arbor, Michigan, United States
University of Michigan Hospital🇺🇸Ann Arbor, Michigan, United States