European Spinocerebellar Ataxia Type 3/Machado*Joseph Disease Initiative

Recruiting

• Conditions: cerebellar dysfunction; disorder of coordination; 10028037

• Registration Number: NL-OMON55616
• Lead Sponsor: eurologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 35

Inclusion Criteria

Patients and carriers with SCA3
18 and older

Exclusion Criteria

Other neurological disorders
Claustrofobia
Metal prosthesis or other metal objects in body
Implanted electronic devices such as a pacemaker

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints:<br /><br>A large cohort of preclinical and mildly ataxic SCA3 mutation carriers, which<br /><br>includes a model of<br /><br>disease evolution in SCA3 and new clinical, motor, imaging and biochemical<br /><br>markers.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>na</p><br>