eft prefrontal activity and the voluntary control of social emotional behaviour

Completed

• Conditions: niet van toepassing; not applicable

• Registration Number: NL-OMON35035
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Healthy, right-handed males aged 18-35 years. All subjects will have normal or corrected-to-normal vision.

Exclusion Criteria

Contra-indications for TMS and fMRI: drug abuse, head trauma, neurological or psychiatric illness, pregnancy, heart disease, claustrophobia, cardiac pacemakers, metal objects in the body, medication pumps, tricyclic antidepressants, neuroleptics and a family history of neurological illness, psychiatric illness or epilepsy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Reaction times and error rates on the approach-avoidance task will be used to<br /><br>test whether the congruency effect in the cTBS condition applied over the vlPFC<br /><br>is larger than in the other TMS conditions. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Aarterial spin labelling during task performance is used to investigate the<br /><br>effects of the different TMS conditions on cerebral blood flow. Moreover,<br /><br>hormonal levels of cortisol and testosterone are measured in order to control<br /><br>for differences in performance on the approach-avoidance-task between subjects. </p><br>