MedPath

COMET: Near-patient testing to guide COPD maintenance treatment in primary care

Not Applicable
Completed
Conditions
Specialty: Primary Care, Primary sub-specialty: Respiratory disorders
UKCRC code/ Disease: Respiratory/ Chronic lower respiratory diseases
Respiratory
Chronic obstructive pulmonary disease
Registration Number
ISRCTN12181464
Lead Sponsor
niversity of Oxford
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
96
Inclusion Criteria

1. Participant is willing and able to give informed consent for participation in the study
2. Male or Female, aged 40 years or above
3. Have a diagnosis of COPD meeting spirometric criteria for diagnosis of COPD (FEV1/FVC ratio <0.7) as recorded in their primary care records

Exclusion Criteria

1. Any previous diagnosis of bronchiectasis, cystic fibrosis, interstitial lung disease, lung cancer, alpha-1 anti-trypsin deficiency or other chronic respiratory disease not related to COPD or asthma
2. Co-existent active diagnosis of asthma (reviewed in the last 2 years)
3. Currently prescribed an ICS, or had a prescription for ICS in the last 2 years
4. Regularly takes oral steroids, or has been regularly taking oral steroids in the last 2 years. Regular use of oral steroids will in general be defined as a longer than 2 week course, although discrete short courses with tapering are acceptable for inclusion.
5. Prior inclusion in a clinical trial of an investigational medicinal product for airways disease in the last 90 days or which may involve administration of oral or inhaled steroid treatment

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath