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Clinical Trials/ISRCTN27914471
ISRCTN27914471
Completed
Not Applicable

A comparison of the efficacy and effectiveness of dihydroartemisinin-piperaquine and artesunate-mefloquine in the treatment of falciparum malaria

Doctors Without Borders (Medecins sans Frontieres [MSF]) (The Netherlands)0 sites640 target enrollmentApril 24, 2006

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Falciparum malaria
Sponsor
Doctors Without Borders (Medecins sans Frontieres [MSF]) (The Netherlands)
Enrollment
640
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 24, 2006
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Doctors Without Borders (Medecins sans Frontieres [MSF]) (The Netherlands)

Eligibility Criteria

Inclusion Criteria

  • 1\. Patients with fever (axillary temperature \>37\.5°C), or a history of fever within 48 hours
  • 2\. Confirmed falciparum malaria (mixed infection P. falciparum with P. vivax and/or P. malariae were included), with more than 500 but less than 100,000 asexual parasites per ml

Exclusion Criteria

  • 1\. Signs of severe and complicated malaria
  • 2\. Children below one\-year\-old
  • 3\. Pregnant women
  • 4\. Patients with a history of taking mefloquine during the previous two months
  • 5\. Patients taken any other antimalarial drugs in the previous 48 hours
  • 6\. Patients with a history of psychiatric diseases

Outcomes

Primary Outcomes

Not specified

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