MedPath

Examining the Impact of an Online, Non-restrictive Diet Among Persons With Multiple Sclerosis

Not Applicable
Completed
Conditions
Multiple Sclerosis
Interventions
Behavioral: 800g Challenge
Registration Number
NCT05712408
Lead Sponsor
University of North Texas, Denton, TX
Brief Summary

The current study aims to test an online, non-restrictive diet among persons with multiple sclerosis (MS). Diet is the number one searched second-line therapy among persons with MS, however there are currently no established dietary approaches to improve health and wellbeing among persons with MS. Participants will complete the 8-week diet program using an online application. The primary research question is whether the diet program is acceptable and can improve general health indicators including cholesterol, glucose, body weight, body fat as well as MS symptoms (i.e., walking, cognition, fatigue, and quality of life).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
16
Inclusion Criteria
  • age 18-70 years
  • a self-reported diagnosis of multiple sclerosis
  • relapse free in past 30 days
  • non-pregnant
  • willing and able to visit University of North Texas on two testing occasions
Exclusion Criteria
  • electronic medical implant, such as a heart pacemaker or an implantable cardioverter defibrillator (ICD)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Diet Intervention800g Challenge8 week non-restrictive diet program
Primary Outcome Measures
NameTimeMethod
Metabolic HealthFrom recruitment to end of 8 week intervention

Fasted Cholesterol and Gloucose

Body FatFrom recruitment to end of 8 week intervention

Change in Body Fat Percentage

Body WeightFrom recruitment to end of 8 week intervention

Change in Body Weight

Secondary Outcome Measures
NameTimeMethod
FatigueFrom recruitment to end of 8 week intervention

Change in Fatigue Severity Scale Scores. Scores range from 1-7 with higher scores indicating greater fatigue.

6-Minute WalkFrom recruitment to end of 8 week intervention

Change in 6-Minute Walk Distance

Cognitive AssessmentsFrom recruitment to end of 8 week intervention

Change in the Brief International Cognitive Assessment in MS Scores. Scores range from 0-208 with higher scores indicating greater cognitive functioning.

Health-Related Quality of LifeFrom recruitment to end of 8 week intervention

Change in SF-12 Scores. Scores range from 0-100 with higher scores indicating greater health-related quality of life.

25-Foot WalkFrom recruitment to end of 8 week intervention

Change in 25-Foot Walk Speed

Trial Locations

Locations (1)

University of North Texas

🇺🇸

Denton, Texas, United States

© Copyright 2025. All Rights Reserved by MedPath