HEPAPAD Study

• Conditions: I70.29; Peripheral vascular disease, unspecified; I73.9

• Registration Number: DRKS00016415
• Lead Sponsor: BT Zotz/Klimas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-12-31
• Study Start: 2020-01-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Peripheral Artery Disease of the AFS or AP, treated by means of blade-PTA; observation period with inclusion of patients 2005 - 2011.

Exclusion Criteria

pregnancy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of re-PTA/stent or peripheral bypass surgery after index-PTA during the observation period of 5 years (2005-2011).

Secondary Outcome Measures

Name	Time	Method
- decreased blood flow by ultrasonography<br>- rate of clinical progression of the PAD (measured by means of decline of the painless walking distance or the Fontaine stage)<br>- association of clinical (arterial hypertension, diabetes, hyperlipidemia, nicotine abuse, BMI, TASC score) and laboratory (fibrinogen, activators of protein C/S, antithrombin, factor VIII, factor V Leiden, prothrombin G20210A, platelet receptor polymorphisms (HPA-1a/b, GPIa807CT), homocysteine, cholesterol, triglycerides, lipoprotein (a)) variables with patency rate in vessels