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Bone Age Determined by Ultrasound (BAUS) in Brazilian Control Children

Conditions
Control, Population
Registration Number
NCT03190109
Lead Sponsor
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Brief Summary

Aiming to validate the use of bone age determined by ultrasound (BAUS) in Brazilian children, normal control students will be studied. X-Ray bone age (RXBA) and BAUS will be determined in 500 children and adolescents of both genders, with chronological age varying from 6-16 years.

Concordance analysis and the correlation between both BA determination methods will be performed.

Detailed Description

Bone age is a valuable method to recognize the maturation status of development and growth. Classical analyses is performed by using the Greulich and Pyle X-Ray measurement. Such analyses have some restrictions such as intra- and inter observer variability, and variable synchronicity of bone maturation.

Bone age determined by ultrasound (BAUS) has been indicated as a fast and reproducible method, allowing decimal BA determination and avoiding the need for X-Ray.

Our aim is to validate the BAUS method in Brazilian normal controls. School students of both genders, with age varying from 6 to 16 years will be included.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
500
Inclusion Criteria
  • absence of chronic illness and drug ingestion
Exclusion Criteria
  • any chronic disease or medicine use
  • body mass index: < -2SDS or > +2SDS
  • stature : < -2SDS or > +2SDS

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
bone age determination by ultrasound (BAUS)chronological ages between 6 and 16 years of age

Determination of bone age in years by employing a ultrasound device

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Santa Casa SP - School of Medical Sciences

🇧🇷

São Paulo, SP, Brazil

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