NCT00587977已完成不适用
ECG-Gated Multidetector CT of Aortic Distensibility FAMRI
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 67
- 试验地点
- 1
- 主要终点
- In year one, this data will be used to develop pulsatility software and test robustness.
研究概览
简要总结
Can software be developed to automatically aid in the measurement of abdominal aortic aneurysms, and is there a way to predict future rupture or growth of abdominal aortic aneurysms.
详细描述
Hypothesis
ECG-gated multidetector CT and ECG-gated Dual Source CT can be used to create multiple volumetric datasets of the abdominal aorta over the time period of the cardiac cycle, allowing for direct and regional calculations of abdominal aortic distensibility over the entire volume of the abdominal aorta, providing insight into risk of abdominal aortic aneurysm rupture and early large vessel stiffness.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •AAA must be at least 3 cm to a maximum 4.9cm cross-sectional diameter.
- •BMI 31 or less.
- •Creatinine results <2.0 and within six months prior to scan.
- •US patients must have only normal creatinine (0.9 to 1.4) for one year before study visit.
- •Patients who are originally scheduled for US, who are then subsequently rolled in this study, will have only a ultrasound scan as followup after the initial CTA.
排除标准
- •Creatinine > 2.
- •Creatinine <0.9 or >1.4 for those who are scheduled for US.
- •Atrial fibrillation or other arrythmia.
- •Known AAA greater than 5 cm in size.
- •Allergy to contrast dye.
结局指标
主要结局
In year one, this data will be used to develop pulsatility software and test robustness.
时间窗: First Year
次要结局
- In year two, the time-resolved CT angiographic datasets from each patient will be analyzed to determine peak AAA pulsatility and peak AAA relative pulsatility (to cross-sectional area within the aneurysm).(Year Two)
研究者
研究点 (1)
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