The role of Omega-3 polyunsaturated fatty acids in the prevention of contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) in chronic kidney disease (CKD) patients
Not Applicable
- Conditions
- renal disease.Nephropathy induced by other drugs, medicaments and biological substances
- Registration Number
- IRCT2016031320441N3
- Lead Sponsor
- Vice chancellor for research, Shiraz University of Medical Sciences, International branch
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Inclusion criteria included chronic kidney disease with GFR 15- 60 ml/min/1.73 m2, the ages of 18 to 80 years, and patients undergoing elective PCI. Exclusion criteria: Pretreatment with N-acetyl cystein or intravenous vitamin C; sensitivity or tolerance to ASA or Clopidogrel or omega-3; sever adverse effects to drugs
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cystatin C. Timepoint: 24 hours after PCI. Method of measurement: kit.;Serum creatinine. Timepoint: 24 hours after PCI. Method of measurement: kit.
- Secondary Outcome Measures
Name Time Method CIN occurrence. Timepoint: 24 hrs after PCI. Method of measurement: based on cystatin C.