Impact of the Introduction of a Gastro-intestinal Panel by Polymerase Chain Reaction (PCR).
- Conditions
- Gastroenteritis
- Registration Number
- NCT03551340
- Lead Sponsor
- University of Lausanne Hospitals
- Brief Summary
Evaluation of the impact of the introduction of multiplex PCR panels on the clinical management of patients with gastroenteritis at the University Hospital of Lausanne, Switzerland.
- Detailed Description
Gastrointestinal multiplex PCR panels have been introduced in clinical practice several years ago, but the impact on the management of patients is yet unknown. The investigators are interested to evaluate if the multiplex PCR panels introduced at the University Hospital of Lausanne in July 2017 modified the usual medical care and in particular the prescription of anti-infectious treatments. The high sensitivity of the multiplex PCR panels should allow a more precise diagnosis of the etiology of the gastrointestinal symptoms of the patients than the traditional methods of stool culture and microscopy. The investigators expect therefore to observe a modification of the proportion of patients receiving anti-infectious treatment, but it is uncertain if it will lead to an increase or a decrease in the use of antibiotics. On one hand antibiotics could be prescribed more often due to a greater and faster detection of enteropathogens. On the other hand antibiotics could be prescribed less often due to more precise diagnosis, showing that viruses and certain bacteria do not require antibiotic treatment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 210
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prescription of antibiotics Within 1 week of availability of stool result Number of patients receiving a prescription of antibiotics depending on the type of investigation
- Secondary Outcome Measures
Name Time Method Number of PCR tests requested. 1 month Number of patients for whom one, two or more PCR tests were requested.
Pathogens identified 1 day Number and types of pathogens identified depending on the type of investigation
Additional investigations 1 week Number of patients who underwent additional investigations within 1 week after reception of the results of the initial investigations
Trial Locations
- Locations (1)
Department of Outpatient Care and Community Medicine, University Hospital of Lausanne
🇨🇭Lausanne, Switzerland
Department of Outpatient Care and Community Medicine, University Hospital of Lausanne🇨🇭Lausanne, Switzerland