The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients

Not Applicable

Completed

• Conditions: Type 2 Diabetes; Healthy Individuals
• Interventions: Dietary Supplement: Branched Chained Amino Acids; Other: Cellulose Placebo mix

• Registration Number: NCT01211717
• Lead Sponsor: Loma Linda University

Brief Summary

The purpose of this study is to determine the effectiveness of the 3 Branched Chained Amino Acids (isoleucine, leucine, and valine) on treating Delayed Onset Muscle Soreness, a type of muscle pain which usually develops after exercising.

Detailed Description

Delayed Onset Muscle Soreness is a common painful sensation experienced by individuals who have been recently inactive and begin with an unaccustomed exercise protocol. Branched Chained Amino Acids have been found as a useful supplement for promoting muscle recovery following exercise; however the effects of this supplement have not been investigated amongst individuals with diabetes.

Study Timeline

• Study First Submitted: 2010-09-28
• Study First Submitted QC: 2010-09-28
• Study First Posted: 2010-09-29
• Study Start: 2010-10
• Primary Completion: 2011-03
• Status Verified: 2011-04
• Study Completion: 2011-04
• Last Update Submitted: 2011-04-21
• Last Update Posted: 2011-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• The subjects with diabetes must have been diagnosed with diabetes at least one year before the onset of the study
• At least 6 weeks of physical inactivity in the upper body
• BMI less than 40

Exclusion Criteria

• For the Diabetics, hemoglobin A1c levels over 13
• Pregnant
• Have Cardiovascular diseases
• Have Hepatic diseases
• Are diagnosed with Rhabdomyolysis
• Recent upper limb injuries
• Upper limb neuropathy
• Blood Pressure levels over 140/90, or lower than 90/60
• Are on High doses of alpha or beta agonist/antagonists, and take any types of NSAID's, Cox 2 inhibitors, Calcium channel blockers, Pre-Gabalin's, or Pain reducers

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Branched Chained Amino Acids	Branched Chained Amino Acids	-
Cellulose mix	Cellulose Placebo mix	-

Primary Outcome Measures

Name	Time	Method
Measuring Pain, using the short form McGill pain questionnaire	5 days following the initial exercise

Secondary Outcome Measures

Name	Time	Method
Measuring Muscle strength of the studied muscle	5 days following the initial exercise

Trial Locations

Locations (1)

Loma Linda University, School of Allied Health Professions; 🇺🇸 Loma Linda, California, United States