The effects of combined Mediterranean, gluten-free, lactose-free and low-FODMAP diets accompanied with supplemental formula, and with the consumption of turmeric in patients with ulcerative colitis.

Phase 2

Recruiting

• Conditions: ulcerative colitis.; Ulcerative colitis, unspecified; K51.9

• Registration Number: IRCT20100524004010N38
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Samples with inflammatory bowel disease confirmed by histopathology The duration of the disease is less than two years The disease is active in a mild to moderate stage (diagnosis of the severity of the disease is the responsibility of the treating physician) Not consuming alcohol and drugs Not suffering from other diseases and intestinal disorders, known autoimmune diseases, cancer, inflammatory and infectious diseases Not using multivitamin-mineral, omega-3, polyphenolic and antioxidant supplements, probiotics as well as the non-use of anticoagulants such as heparin and warfarin, NSAIDs such as ibuprofen, aspirin and diclofenac, antihistamines and calcium channel antagonists such as nifedipine in the past month BMI over 18.5 and under 30 Age 18 years and above No change in the type and dosage of the drug consumed during the past month Not having clinically diagnosed psychiatric disorders that impair the patient's ability to provide written informed consent Willingness to participate in the study

Exclusion Criteria

Recurrence of the disease in a way that leads to the hospitalization of the patient Suffering from other diseases such as biliary disease, kidney diseases, known autoimmune diseases, cancer and liver disorders The presence of abscesses or abdominal fistulas A history of ileostomy and colostomy Pregnancy or breastfeeding in women or Using birth control pills Receiving tube or intravenous feeding Following special diets and vegetarianism during the last 3 months Unwillingness to continue cooperation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum hs-CRP. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa.;TNF-a. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa.;TAC. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa.;Life Quality. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Questionnaire.;Disease Activity Index. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Questionnaire.

Secondary Outcome Measures

Name	Time	Method
Weight. Timepoint: At the first of research and end of research( 6th week). Method of measurement: scale.;BMI. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Calculation.