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Clinical Trials/NCT01237145
NCT01237145
Completed
Not Applicable

Study to Determine the Immune Response From Broncho-alveolar Cells Against Pigeon Specific Antigens

Bossink, A.W.J.1 site in 1 country10 target enrollmentSeptember 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Extrinsic Allergic Alveolitis
Sponsor
Bossink, A.W.J.
Enrollment
10
Locations
1
Primary Endpoint
ELISPOT response in cells obtained from broncho-alveolar lavage
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The purpose of this study is to establish if cells present in lung tissue during extrinsic allergic alveolitis (EAA) are able to elicit an immune response against specific antigens. The hypothesis is: cells in BAL lavage fluid from patients with EAA will be responsive to specific antigens and this response can be measured using ELISPOT.

Detailed Description

Subjects suffering from extrinsic allergic alveolitis caused by pigeons will undergo a broncho alveolar lavage. Cells obtained from this BAL will be used for ELISPOT technique with pigeon specific antigens

Registry
clinicaltrials.gov
Start Date
September 2011
End Date
December 2012
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Bossink, A.W.J.
Responsible Party
Principal Investigator
Principal Investigator

A.W.J.Bossink

Dr

Bossink, A.W.J.

Eligibility Criteria

Inclusion Criteria

  • suspicion of pigeon induced extrinsic alveolitis

Exclusion Criteria

  • use of oral steroids
  • unable to give informed consent
  • age below 18

Outcomes

Primary Outcomes

ELISPOT response in cells obtained from broncho-alveolar lavage

Time Frame: 2 days

All elispots will be performed the same day, the end point will be available the next day

Secondary Outcomes

  • Elispot response in cells from blood(2 days)

Study Sites (1)

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