Ventilation strategies in anaesthetised cardiac surgical patients.

Not Applicable

Completed

• Conditions: Cardiac surgery; Mechanical ventilation; Surgery - Other surgery; Anaesthesiology - Anaesthetics; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12616000146493
• Lead Sponsor: Departments of Intensive Care and Anaesthesia, Austin Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Patients will be eligible to participate in this study if:
1. The patient is aged 18 years or older
2. The patient is undergoing elective coronary artery bypass surgery requiring harvesting of the left internal mammary artery as part of standard of care
3. The patient will have an arterial line inserted for routine monitoring of blood pressure during the surgical procedure
4. The patient will have transoesophageal echocardiography as routine standard of care.

Exclusion Criteria

Patients will be ineligible for participation if:
1. The patient is less than 18 years
2. The patient is undergoing emergency coronary artery bypass surgery
3. The patient is undergoing a non-coronary artery bypass surgery
4. The patient has chronic lung disease (KCO/TLCO/FEV1 <50% predicted)
5. The patient has moderate pulmonary hypertension (MPA >40mmHg)
6. The patient has super obesity (BMI>50kg/m2)
7. The patient is pregnant.
8. The patient has an ASA (American Society of Anesthesiologists) physical status V

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Arterial partial pressure of carbon dioxide <br><br>This variable will be measured via an ABL Blood Gas Analyzer. [At baseline, then 3 minutes, 6 minutes, 9 minutes, 12 minutes, and 15 minutes whilst the surgeons are harvesting the left internal mammary artery..]