3D Printed Donor Tooth Replica in Autotransplantation of Teeth

Not Applicable

• Conditions: Decayed Teeth
• Interventions: Procedure: 3D printed replica of the donor tooth; Procedure: Conventional Autotransplantation of tooth

• Registration Number: NCT04933409
• Lead Sponsor: College of Medical Sciences Teaching Hospital. Nepal

Brief Summary

3D printed replicas of the donor tooth can reduce extraoral time during the autotransplantation of teeth, which can reduce dehydration and manipulation of periodontal tissue of the donor tooth, thus possibly increasing the success rate.

Detailed Description

This technique of autotransplantation has been innovated using 3-dimensional (3D) imaging and rapid prototyping.The use of a 3D-printed replica of the donor tooth is thought to minimize the risk of iatrogenic damage to the actual donor tooth. Nevertheless, no large prospective and comparative studies are available to assess the outcomes using these 3D techniques. Therefore, this study aimed to compare 3D printed replicas in autotransplantation of teeth, compared to the conventional technique. The present study will evaluate the feasibility, clinical satisfied accuracy, and stability of a novel approach for computer-aided autotransplantation of teeth. This new approach facilitated the surgical procedure and might be a viable and predictable method for autotransplantation of teeth.

Application of printed 3D replicas of transplanted teeth facilitates surgical preparation of the recipient site, shortens the extra-alveolar time, and reduces the minimum the number of attempts of the donor tooth insertion at the prepared socket. Their use can significantly decrease the risk of damage to the root surface of a transplant, thus increasing the chance of success.

Study Timeline

• Study First Submitted: 2021-06-17
• Study First Submitted QC: 2021-06-17
• Study First Posted: 2021-06-21
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-02
• Last Update Posted: 2021-09-05
• Study Start: 2021-10-01
• Primary Completion: 2021-12-01
• Study Completion: 2022-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. patient presenting with decayed first molars
2. autotransplantation of third molar at the recipient site

Exclusion Criteria

1. Diabetic, pregnant patients
2. other autotransplantations (other than first molar recipient and third molar donor)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
3D printed replica of Donor tooth	3D printed replica of the donor tooth	3D printed replica of Donor tooth
Conventional	Conventional Autotransplantation of tooth	Conventional method of autotransplantation.

Primary Outcome Measures

Name	Time	Method
Operative time	1 day	Operative time from the start of socket preparation at the recipient site
Rate of Ankylosis (replacement resorption)	6 months	Ankylosis (replacement resorption)
Rate of root resorption	6 months	infection related root resorption
Number of teeth that fail	two weeks	reduced mobility (less than grade II) after 2 weeks of autotransplantation

Secondary Outcome Measures

Name	Time	Method
Cost difference of the treatment	1 day	Cost of 3D printing